LITTLE KNOWN FACTS ABOUT PHENOBARBITAL SODIUM WATER SOLUBILITY.

pentobarbital will lower the extent or effect of oliceridine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. If coadministration with a CYP3A4 inducer is important, consider raising oliceridine dose right up until stable drug effects are reached; watch for signs of opioid withdrawal.pentobarbital will lessen the exten